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Meiosis Script Emerson Crew Bobby Rich Interphase: In interphase, the cell has homologous chromosomes from both their parents. During this phase. The chromosomes are duplicated, along with the Centrosomes, and become sister chromatids, which brings us to Prophase. Prophase I : The sister chromatids make their way to each other and start undergoing synapsis, this is when the chromosomes start crossing over parts of their chromosomes to gain genetic variation. Metaphase: Now that the chromosomes have genetic variation, they start to line up at the cell's equator and prepare to be split into two cells. However, the way they orient themselves is also important. One of the chromosomes could be on the left instead of the right, changing the genetics completely. With two pairs of chromosomes, there are just four different combinations, but accounting for the fact that there are 23 chromosomes in humans, there are so many possible combinations, creating tons of genetic variation. Anaphase: Just like regular mitosis, the centrosomes attach to the oriented chromosomes, they do not split the sister chromosomes though, they just pull them to the other sides of the cells. Telophase: The chromosomes make their way to the other side of the cell during Telophase, where they make new nuclei and split the cell, keeping one centrosome with them. Prophase II: In Prophase II, the nuclei disappear again, and the chromosomes bundle back up, they duplicate the centromeres in each cell, giving 2 for each cell. The chromosomes do not cross over in the phase like last time, instead, they move to the middle of the cell. Metaphase II: In Metaphase, the chromosomes move to the middle of the cell again, and the spindle fibers from the centromeres attach to each of the chromosomes, Anaphase II: By Anaphase II, the mixed-up sister chromosomes split and get pulled to both ends of the cell, where they start Telophase II Telophase II: The cells split for the final time in meiosis. The resulting cells are very different from the starting cells. At the start, the original cell had 2 pairs of chromosomes that were from both of the parents. In the end, we have 4 genetically differing cells with one pair of chromosomes each, all of them being mixed from the mother and father cells. Meiosis is a very interesting process that is meant to make a lot of variation between the offspring. The mixing of the genes from the parents, the independent assortment, and then just mutations can add up to trillions of combinations of genes just for this one person.
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